Generation of a highly diverse panel of antagonistic chicken monoclonal antibodies against the GIP receptor

Raising functional antibodies against G protein-coupled receptors (GPCRs) is challenging due to their low density expression, instability in the absence of the cell membrane's lipid bilayer and frequently short extracellular domains that can serve as antigens. In addition, a particular therapeu...

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Detalles Bibliográficos
Autores principales: Könitzer, Jennifer D., Pramanick, Shreya, Pan, Qi, Augustin, Robert, Bandholtz, Sebastian, Harriman, William, Izquierdo, Shelley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384726/
https://www.ncbi.nlm.nih.gov/pubmed/28055305
http://dx.doi.org/10.1080/19420862.2016.1276683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384726/
https://www.ncbi.nlm.nih.gov/pubmed/28055305
http://dx.doi.org/10.1080/19420862.2016.1276683

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