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Generation of a highly diverse panel of antagonistic chicken monoclonal antibodies against the GIP receptor
Raising functional antibodies against G protein-coupled receptors (GPCRs) is challenging due to their low density expression, instability in the absence of the cell membrane's lipid bilayer and frequently short extracellular domains that can serve as antigens. In addition, a particular therapeu...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384726/ https://www.ncbi.nlm.nih.gov/pubmed/28055305 http://dx.doi.org/10.1080/19420862.2016.1276683 |