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A strategy to identify linker-based modules for the allosteric regulation of antibody-antigen binding affinities of different scFvs

Antibody single-chain variable fragments (scFvs) are used in a variety of applications, such as for research, diagnosis and therapy. Essential for these applications is the extraordinary specificity, selectivity and affinity of antibody paratopes, which can also be used for efficient protein purific...

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Detalles Bibliográficos
Autores principales: Kellmann, Sarah-Jane, Dübel, Stefan, Thie, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384732/
https://www.ncbi.nlm.nih.gov/pubmed/28055297
http://dx.doi.org/10.1080/19420862.2016.1277302