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A strategy to identify linker-based modules for the allosteric regulation of antibody-antigen binding affinities of different scFvs
Antibody single-chain variable fragments (scFvs) are used in a variety of applications, such as for research, diagnosis and therapy. Essential for these applications is the extraordinary specificity, selectivity and affinity of antibody paratopes, which can also be used for efficient protein purific...
Autores principales: | Kellmann, Sarah-Jane, Dübel, Stefan, Thie, Holger |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384732/ https://www.ncbi.nlm.nih.gov/pubmed/28055297 http://dx.doi.org/10.1080/19420862.2016.1277302 |
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