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Fetuin-A deficiency protects mice from Experimental Autoimmune Encephalomyelitis (EAE) and correlates with altered innate immune response

Fetuin-A is a biomarker of disease activity in multiple sclerosis. Our aim was to investigate whether Fetuin-A plays a direct role in the neuroinflammatory response in the mouse EAE model. Peak Fetuin-A expression in the CNS and in peripheral lymphoid tissue correlated with peak EAE disease activity...

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Detalles Bibliográficos
Autores principales: Harris, Violaine K., Bell, Lena, Langan, Ruth-Anne, Tuddenham, John, Landy, Mark, Sadiq, Saud A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384772/
https://www.ncbi.nlm.nih.gov/pubmed/28388685
http://dx.doi.org/10.1371/journal.pone.0175575