Cargando…

Genome mining unearths a hybrid nonribosomal peptide synthetase-like-pteridine synthase biosynthetic gene cluster

Nonribosomal peptides represent a large class of metabolites with pharmaceutical relevance. Pteridines, such as pterins, folates, and flavins, are heterocyclic metabolites that often serve as redox-active cofactors. The biosynthetic machineries for construction of these distinct classes of small mol...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Hyun Bong, Perez, Corey E, Barber, Karl W, Rinehart, Jesse, Crawford, Jason M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384830/
https://www.ncbi.nlm.nih.gov/pubmed/28431213
http://dx.doi.org/10.7554/eLife.25229