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Genome mining unearths a hybrid nonribosomal peptide synthetase-like-pteridine synthase biosynthetic gene cluster
Nonribosomal peptides represent a large class of metabolites with pharmaceutical relevance. Pteridines, such as pterins, folates, and flavins, are heterocyclic metabolites that often serve as redox-active cofactors. The biosynthetic machineries for construction of these distinct classes of small mol...
Autores principales: | Park, Hyun Bong, Perez, Corey E, Barber, Karl W, Rinehart, Jesse, Crawford, Jason M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384830/ https://www.ncbi.nlm.nih.gov/pubmed/28431213 http://dx.doi.org/10.7554/eLife.25229 |
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