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Establishment of a new initial dose plan for vancomycin using the generalized linear mixed model
BACKGROUND: When administering vancomycin hydrochloride (VCM), the initial dose is adjusted to ensure that the steady-state trough value (Css-trough) remains within the effective concentration range. However, the Css-trough (population mean method predicted value [PMMPV]) calculated using the popula...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385004/ https://www.ncbi.nlm.nih.gov/pubmed/28388921 http://dx.doi.org/10.1186/s12976-017-0054-9 |