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Establishment of a new initial dose plan for vancomycin using the generalized linear mixed model

BACKGROUND: When administering vancomycin hydrochloride (VCM), the initial dose is adjusted to ensure that the steady-state trough value (Css-trough) remains within the effective concentration range. However, the Css-trough (population mean method predicted value [PMMPV]) calculated using the popula...

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Detalles Bibliográficos
Autores principales:	Kourogi, Yasuyuki, Ogata, Kenji, Takamura, Norito, Tokunaga, Jin, Setoguchi, Nao, Kai, Mitsuhiro, Tanaka, Emi, Chiyotanda, Susumu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385004/ https://www.ncbi.nlm.nih.gov/pubmed/28388921 http://dx.doi.org/10.1186/s12976-017-0054-9

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