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Pre-incubation with hucMSC-exosomes prevents cisplatin-induced nephrotoxicity by activating autophagy

BACKGROUND: The administration of cisplatin is limited due to its nephrotoxic side effects, and prevention of this nephrotoxicity of cisplatin is difficult. Mesenchymal stem cell (MSC)-derived exosomes have been implicated as a novel therapeutic approach for tissue injury. In this study, we demonstr...

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Detalles Bibliográficos
Autores principales: Wang, Bingying, Jia, Haoyuan, Zhang, Bin, Wang, Juanjuan, Ji, Cheng, Zhu, Xueming, Yan, Yongmin, Yin, Lei, Yu, Jing, Qian, Hui, Xu, Wenrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385032/
https://www.ncbi.nlm.nih.gov/pubmed/28388958
http://dx.doi.org/10.1186/s13287-016-0463-4