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Impact of matrix metalloproteinase 9 rs3918242 genetic variant on lipid-lowering efficacy of simvastatin therapy in Chinese patients with coronary heart disease

BACKGROUND: Genetic variation of matrix metalloproteinase 9 (MMP-9) gene polymorphism has been suggested to modulate coronary heart diseases (CHD), yet the underlying mechanisms are not well understood. METHODS: We investigated the association of MMP9 rs3918242 single nucleotide polymorphism with in...

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Detalles Bibliográficos
Autores principales: Xu, Yuanyuan, Wang, Yan, Zhi, Jixin, Qi, Lichun, Zhang, Tong, Li, Xueqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385050/
https://www.ncbi.nlm.nih.gov/pubmed/28390432
http://dx.doi.org/10.1186/s40360-017-0132-y