LEAPS Vaccine Incorporating HER-2/neu Epitope Elicits Protection That Prevents and Limits Tumor Growth and Spread of Breast Cancer in a Mouse Model

The prototype J-LEAPS T cell vaccine for HER-2/neu breast cancer (J-HER) consists of the murine HER-2/neu(66–74) H-2(d) CD8 T cell epitope covalently attached through a triglycine linker to the J-immune cell binding ligand (ICBL) (human β2 microglobulin(38–50) peptide). The J-ICBL was chosen for its...

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Detalles Bibliográficos
Autores principales: Rosenthal, Ken S., Stone, Sarah, Koski, Gary, Zimmerman, Daniel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385252/
https://www.ncbi.nlm.nih.gov/pubmed/28459074
http://dx.doi.org/10.1155/2017/3613505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385252/
https://www.ncbi.nlm.nih.gov/pubmed/28459074
http://dx.doi.org/10.1155/2017/3613505

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