A Linear Temporal Increase in Thrombin Activity and Loss of Its Receptor in Mouse Brain following Ischemic Stroke

BACKGROUND: Brain thrombin activity is increased following acute ischemic stroke and may play a pathogenic role through the protease-activated receptor 1 (PAR1). In order to better assess these factors, we obtained a novel detailed temporal and spatial profile of thrombin activity in a mouse model o...

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Detalles Bibliográficos
Autores principales: Bushi, Doron, Stein, Efrat Shavit, Golderman, Valery, Feingold, Ekaterina, Gera, Orna, Chapman, Joab, Tanne, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385331/
https://www.ncbi.nlm.nih.gov/pubmed/28443061
http://dx.doi.org/10.3389/fneur.2017.00138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385331/
https://www.ncbi.nlm.nih.gov/pubmed/28443061
http://dx.doi.org/10.3389/fneur.2017.00138

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