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On the Molecular Evolution of Leptin, Leptin Receptor, and Endospanin

Over a decade passed between Friedman’s discovery of the mammalian leptin gene (1) and its cloning in fish (2) and amphibians (3). Since 2005, the concept of gene synteny conservation (vs. gene sequence homology) was instrumental in identifying leptin genes in dozens of species, and we now have lept...

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Detalles Bibliográficos
Autores principales: Londraville, Richard Lyle, Prokop, Jeremy W., Duff, Robert Joel, Liu, Qin, Tuttle, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385356/
https://www.ncbi.nlm.nih.gov/pubmed/28443063
http://dx.doi.org/10.3389/fendo.2017.00058