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The High Calcium, High Phosphorus Rescue Diet Is Not Suitable to Prevent Secondary Hyperparathyroidism in Vitamin D Receptor Deficient Mice

The vitamin D receptor (VDR) knockout (KO) mouse is a common model to unravel novel metabolic functions of vitamin D. It is recommended to feed these mice a high calcium (2%), high phosphorus (1.25%) diet, termed rescue diet (RD) to prevent hypocalcaemia and secondary hyperparathyroidism. First, we...

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Detalles Bibliográficos
Autores principales: Grundmann, Sarah M., Brandsch, Corinna, Rottstädt, Daniela, Kühne, Hagen, Stangl, Gabriele I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385385/
https://www.ncbi.nlm.nih.gov/pubmed/28443031
http://dx.doi.org/10.3389/fphys.2017.00212