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HMGB1 release by H(2)O(2)-induced hepatocytes is regulated through calcium overload and 58-F interference

HMGB1 is passively released by injured or dying cells and aggravates inflammatory processes. The release of HMGB1 and calcium overload have each been reported to be important mediators of H(2)O(2)-induced injury. However, a potential connection between these two processes remains to be elucidated. I...

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Detalles Bibliográficos
Autores principales: Zhao, Pei, Ye, Tingjie, Yan, Xiaofeng, Hu, Xudong, Liu, Ping, Wang, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385391/
https://www.ncbi.nlm.nih.gov/pubmed/28417016
http://dx.doi.org/10.1038/cddiscovery.2017.8