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Notch signaling mediated by TGF-β/Smad pathway in concanavalin A-induced liver fibrosis in rats

AIM: To explore the exact interaction between Notch and transforming growth factor (TGF)-β signaling in liver fibrosis. METHODS: We established a rat model of liver fibrosis induced by concanavalin A. Peripheral blood mononuclear cells (PBMCs) were isolated from the modeled rats, and cultured with γ...

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Detalles Bibliográficos
Autores principales: Wang, Yi, Shen, Ruo-Wu, Han, Bing, Li, Zhen, Xiong, Le, Zhang, Feng-Yu, Cong, Bei-Bei, Zhang, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385399/
https://www.ncbi.nlm.nih.gov/pubmed/28428712
http://dx.doi.org/10.3748/wjg.v23.i13.2330