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Notch signaling mediated by TGF-β/Smad pathway in concanavalin A-induced liver fibrosis in rats
AIM: To explore the exact interaction between Notch and transforming growth factor (TGF)-β signaling in liver fibrosis. METHODS: We established a rat model of liver fibrosis induced by concanavalin A. Peripheral blood mononuclear cells (PBMCs) were isolated from the modeled rats, and cultured with γ...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385399/ https://www.ncbi.nlm.nih.gov/pubmed/28428712 http://dx.doi.org/10.3748/wjg.v23.i13.2330 |