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Galectin-1 inhibition attenuates profibrotic signaling in hypoxia-induced pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is characterized by lung remodeling arising from epithelial injury, aberrant fibroblast growth, and excessive deposition of extracellular matrix. Repeated epithelial injury elicits abnormal wound repair and lung remodeling, often associated with alveolar collapse...

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Detalles Bibliográficos
Autores principales: Kathiriya, Jaymin J, Nakra, Niyati, Nixon, Jenna, Patel, Puja S, Vaghasiya, Vijay, Alhassani, Ahmed, Tian, Zhi, Allen-Gipson, Diane, Davé, Vrushank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385413/
https://www.ncbi.nlm.nih.gov/pubmed/28417017
http://dx.doi.org/10.1038/cddiscovery.2017.10