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Galectin-1 inhibition attenuates profibrotic signaling in hypoxia-induced pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is characterized by lung remodeling arising from epithelial injury, aberrant fibroblast growth, and excessive deposition of extracellular matrix. Repeated epithelial injury elicits abnormal wound repair and lung remodeling, often associated with alveolar collapse...
Autores principales: | Kathiriya, Jaymin J, Nakra, Niyati, Nixon, Jenna, Patel, Puja S, Vaghasiya, Vijay, Alhassani, Ahmed, Tian, Zhi, Allen-Gipson, Diane, Davé, Vrushank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385413/ https://www.ncbi.nlm.nih.gov/pubmed/28417017 http://dx.doi.org/10.1038/cddiscovery.2017.10 |
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