Overexpression of the ATPase Inhibitory Factor 1 Favors a Non-metastatic Phenotype in Breast Cancer

Partial suppression of mitochondrial oxidative phosphorylation and the concurrent activation of aerobic glycolysis is a hallmark of proliferating cancer cells. Overexpression of the ATPase inhibitory factor 1 (IF1), an in vivo inhibitor of the mitochondrial ATP synthase, is observed in most prevalen...

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Detalles Bibliográficos
Autores principales: García-Ledo, Lucía, Nuevo-Tapioles, Cristina, Cuevas-Martín, Carmen, Martínez-Reyes, Inmaculada, Soldevilla, Beatriz, González-Llorente, Lucía, Cuezva, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385467/
https://www.ncbi.nlm.nih.gov/pubmed/28443245
http://dx.doi.org/10.3389/fonc.2017.00069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385467/
https://www.ncbi.nlm.nih.gov/pubmed/28443245
http://dx.doi.org/10.3389/fonc.2017.00069

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