Cargando…
Overexpression of the ATPase Inhibitory Factor 1 Favors a Non-metastatic Phenotype in Breast Cancer
Partial suppression of mitochondrial oxidative phosphorylation and the concurrent activation of aerobic glycolysis is a hallmark of proliferating cancer cells. Overexpression of the ATPase inhibitory factor 1 (IF1), an in vivo inhibitor of the mitochondrial ATP synthase, is observed in most prevalen...
Autores principales: | García-Ledo, Lucía, Nuevo-Tapioles, Cristina, Cuevas-Martín, Carmen, Martínez-Reyes, Inmaculada, Soldevilla, Beatriz, González-Llorente, Lucía, Cuezva, José M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385467/ https://www.ncbi.nlm.nih.gov/pubmed/28443245 http://dx.doi.org/10.3389/fonc.2017.00069 |
Ejemplares similares
-
Overexpression of Mitochondrial IF1 Prevents Metastatic Disease of Colorectal Cancer by Enhancing Anoikis and Tumor Infiltration of NK Cells
por: González-Llorente, Lucía, et al.
Publicado: (2019) -
Regulation of the H(+)-ATP synthase by IF1: a role in mitohormesis
por: Esparza-Moltó, Pau B., et al.
Publicado: (2017) -
IF1 promotes oligomeric assemblies of sluggish ATP synthase and outlines the heterogeneity of the mitochondrial membrane potential
por: Romero-Carramiñana, Inés, et al.
Publicado: (2023) -
Vacuolar Membrane ATPase Activity 21 Predicts a Favorable Outcome and Acts as a Suppressor in Colorectal Cancer
por: Zhang, Fan, et al.
Publicado: (2021) -
Expression, regulation and clinical relevance of the ATPase inhibitory factor 1 in human cancers
por: Sánchez-Aragó, M, et al.
Publicado: (2013)