Association of C-Type Lectin Mincle with FcεRIβγ Subunits Leads to Functional Activation of RBL-2H3 Cells through Syk

Macrophage-inducible C-type lectin (Mincle) interacts with the γ-subunit of high-affinity IgE receptor (FcεRIγ) and activates Syk by recognizing its specific ligand, trehalose-6,6′-dimycolate, a glycolipid produced by Mycobacterium tuberculosis. It has been suggested that mast cells participate in t...

Descripción completa

Detalles Bibliográficos
Autores principales: Honjoh, Chisato, Chihara, Kazuyasu, Yoshiki, Hatsumi, Yamauchi, Shota, Takeuchi, Kenji, Kato, Yuji, Hida, Yukio, Ishizuka, Tamotsu, Sada, Kiyonao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385489/
https://www.ncbi.nlm.nih.gov/pubmed/28393919
http://dx.doi.org/10.1038/srep46064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385489/
https://www.ncbi.nlm.nih.gov/pubmed/28393919
http://dx.doi.org/10.1038/srep46064

Ejemplares similares