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Association of C-Type Lectin Mincle with FcεRIβγ Subunits Leads to Functional Activation of RBL-2H3 Cells through Syk

Macrophage-inducible C-type lectin (Mincle) interacts with the γ-subunit of high-affinity IgE receptor (FcεRIγ) and activates Syk by recognizing its specific ligand, trehalose-6,6′-dimycolate, a glycolipid produced by Mycobacterium tuberculosis. It has been suggested that mast cells participate in t...

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Detalles Bibliográficos
Autores principales:	Honjoh, Chisato, Chihara, Kazuyasu, Yoshiki, Hatsumi, Yamauchi, Shota, Takeuchi, Kenji, Kato, Yuji, Hida, Yukio, Ishizuka, Tamotsu, Sada, Kiyonao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385489/ https://www.ncbi.nlm.nih.gov/pubmed/28393919 http://dx.doi.org/10.1038/srep46064

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