Metabolomic characterisation of the effects of oncogenic PIK3CA transformation in a breast epithelial cell line

Somatic mutations in PIK3CA are frequently found in a number of human cancers, including breast cancer, altering cellular physiology and tumour sensitivity to chemotherapy. This renders PIK3CA an attractive molecular target for early detection and personalised therapy. Using (1)H Nuclear Magnetic Re...

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Detalles Bibliográficos
Autores principales: Lau, Chung-Ho E., Tredwell, Gregory D., Ellis, James K., Lam, Eric W.-F., Keun, Hector C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385542/
https://www.ncbi.nlm.nih.gov/pubmed/28393905
http://dx.doi.org/10.1038/srep46079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385542/
https://www.ncbi.nlm.nih.gov/pubmed/28393905
http://dx.doi.org/10.1038/srep46079

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