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Artemisinin protects PC12 cells against β-amyloid-induced apoptosis through activation of the ERK1/2 signaling pathway

Accumulating evidence displays that an abnormal deposition of amyloid beta-peptide (Aβ) is the primary cause of the pathogenesis of Alzheimer's disease (AD). And therefore the elimination of Aβ is regarded as an important strategy for AD treatment. The discovery of drug candidates using culture...

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Detalles Bibliográficos
Autores principales: Zeng, Zhiwen, Xu, Jinying, Zheng, Wenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385605/
https://www.ncbi.nlm.nih.gov/pubmed/28391183
http://dx.doi.org/10.1016/j.redox.2017.04.003