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Visualization of aging-associated chromatin alterations with an engineered TALE system

Visualization of specific genomic loci in live cells is a prerequisite for the investigation of dynamic changes in chromatin architecture during diverse biological processes, such as cellular aging. However, current precision genomic imaging methods are hampered by the lack of fluorescent probes wit...

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Detalles Bibliográficos
Autores principales: Ren, Ruotong, Deng, Liping, Xue, Yanhong, Suzuki, Keiichiro, Zhang, Weiqi, Yu, Yang, Wu, Jun, Sun, Liang, Gong, Xiaojun, Luan, Huiqin, Yang, Fan, Ju, Zhenyu, Ren, Xiaoqing, Wang, Si, Tang, Hong, Geng, Lingling, Zhang, Weizhou, Li, Jian, Qiao, Jie, Xu, Tao, Qu, Jing, Liu, Guang-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385610/
https://www.ncbi.nlm.nih.gov/pubmed/28139645
http://dx.doi.org/10.1038/cr.2017.18