Catalytic Asymmetric Formal Total Synthesis of (−)-Triptophenolide and (+)-Triptolide

ABSTRACT: Catalytic asymmetric formal synthesis of (−)-Triptophenolide and (+)-Triptolide have been achieved. Key reaction involves Palladium catalyzed asymmetric conjugate addition of aryl boronic acid to 3-methyl cyclohexe-1-none to form quaternary carbon. Claisen rearrangement and subsequent aldo...

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Detalles Bibliográficos
Autores principales: Xu, Wen-Dan, Li, Liang-Qun, Li, Ming-Ming, Geng, Hui-Chun, Qin, Hong-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385656/
https://www.ncbi.nlm.nih.gov/pubmed/27095015
http://dx.doi.org/10.1007/s13659-016-0100-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385656/
https://www.ncbi.nlm.nih.gov/pubmed/27095015
http://dx.doi.org/10.1007/s13659-016-0100-z

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