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Anomalous altered expressions of downstream gene-targets in TP53-miRNA pathways in head and neck cancer

The prevalence of head and neck squamous cell carcinoma, HNSCC, continues to grow. Change in the expression of TP53 in HNSCC affects its downstream miRNAs and their gene targets, anomalously altering the expressions of the five genes, MEIS1, AGTR1, DTL, TYMS and BAK1. These expression alterations fo...

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Detalles Bibliográficos
Autores principales: Mitra, Sanga, Mukherjee, Nupur, Das, Smarajit, Das, Pijush, Panda, Chinmay Kumar, Chakrabarti, Jayprokas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385823/
https://www.ncbi.nlm.nih.gov/pubmed/25186767
http://dx.doi.org/10.1038/srep06280