Progressive slowdown/prevention of cellular senescence by CD9-targeted delivery of rapamycin using lactose-wrapped calcium carbonate nanoparticles

Cellular senescence, a state of irreversible growth arrest and altered cell function, causes aging-related diseases. Hence, treatment modalities that could target aging cells would provide a robust therapeutic avenue. Herein, for the first time, we utilized CD9 receptors (overexpressed in senescent...

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Detalles Bibliográficos
Autores principales: Thapa, Raj Kumar, Nguyen, Hanh Thuy, Jeong, Jee-Heon, Kim, Jae Ryong, Choi, Han-Gon, Yong, Chul Soon, Kim, Jong Oh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385881/
https://www.ncbi.nlm.nih.gov/pubmed/28393891
http://dx.doi.org/10.1038/srep43299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385881/
https://www.ncbi.nlm.nih.gov/pubmed/28393891
http://dx.doi.org/10.1038/srep43299

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