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Sevoflurane decreases self-renewal capacity and causes c-Jun N-terminal kinase–mediated damage of rat fetal neural stem cells

Increasing studies have demonstrated that sevoflurane can induce neurotoxicity in the developing brains. JNK normally promotes apoptosis. It was hypothesized that sevoflurane affected the proliferation and differentiation of FNSCs and induced cell apoptosis, which caused the learning and memory defi...

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Detalles Bibliográficos
Autores principales: Yang, Zeyong, Lv, Jingjing, Li, Xingxing, Meng, Qiong, Yang, Qiling, Ma, Wei, Li, Yuanhai, Ke, Zun Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385884/
https://www.ncbi.nlm.nih.gov/pubmed/28393934
http://dx.doi.org/10.1038/srep46304