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Suppression of Retinal Neovascularization by Inhibition of Galectin-1 in a Murine Model of Oxygen-Induced Retinopathy

Galectin-1 (Gal-1) has been proved to be an important factor in the process of tumor angiogenesis recently. As a small molecule, OTX008 serves as a selective inhibitor of Gal-1. In this study, the role of Gal-1 and the antiangiogenic effect of OTX008 on retinal neovascularization (RNV) were investig...

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Detalles Bibliográficos
Autores principales: Yang, Ning, Zhang, Wenxi, He, Tao, Xing, Yiqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385917/
https://www.ncbi.nlm.nih.gov/pubmed/28428895
http://dx.doi.org/10.1155/2017/5053035