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An intramolecular interaction within the lipid kinase Fab1 regulates cellular phosphatidylinositol 3,5-bisphosphate lipid levels

Phosphorylated phosphoinositide lipids (PPIs) are low-abundance signaling molecules that control signal transduction pathways and are necessary for cellular homeostasis. The PPI phosphatidylinositol (3,5)-bisphosphate (PI(3,5)P(2)) is essential in multiple organ systems. PI(3,5)P(2) is generated fro...

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Detalles Bibliográficos
Autores principales: Lang, Michael J., Strunk, Bethany S., Azad, Nadia, Petersen, Jason L., Weisman, Lois S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385934/
https://www.ncbi.nlm.nih.gov/pubmed/28148651
http://dx.doi.org/10.1091/mbc.E16-06-0390