Vamp-7–dependent secretion at the immune synapse regulates antigen extraction and presentation in B-lymphocytes

Recognition of surface-tethered antigens (Ags) by B-cells leads to the formation of an immune synapse that promotes Ag uptake for presentation onto MHC-II molecules. Extraction of immobilized Ags at the immune synapse of B-cells relies on the local secretion of lysosomes, which are recruited to the...

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Detalles Bibliográficos
Autores principales: Obino, Dorian, Diaz, Jheimmy, Sáez, Juan José, Ibañez-Vega, Jorge, Sáez, Pablo J., Alamo, Martina, Lankar, Danielle, Yuseff, Maria-Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385938/
https://www.ncbi.nlm.nih.gov/pubmed/28179460
http://dx.doi.org/10.1091/mbc.E16-10-0722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385938/
https://www.ncbi.nlm.nih.gov/pubmed/28179460
http://dx.doi.org/10.1091/mbc.E16-10-0722

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