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Vamp-7–dependent secretion at the immune synapse regulates antigen extraction and presentation in B-lymphocytes
Recognition of surface-tethered antigens (Ags) by B-cells leads to the formation of an immune synapse that promotes Ag uptake for presentation onto MHC-II molecules. Extraction of immobilized Ags at the immune synapse of B-cells relies on the local secretion of lysosomes, which are recruited to the...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385938/ https://www.ncbi.nlm.nih.gov/pubmed/28179460 http://dx.doi.org/10.1091/mbc.E16-10-0722 |