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Dual function of TGFβ in lens epithelial cell fate: implications for secondary cataract

The most common vision-disrupting complication of cataract surgery is posterior capsule opacification (PCO; secondary cataract). PCO is caused by residual lens cells undergoing one of two very different cell fates: either transdifferentiating into myofibroblasts or maturing into lens fiber cells. Al...

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Detalles Bibliográficos
Autores principales: Boswell, Bruce A., Korol, Anna, West-Mays, Judith A., Musil, Linda S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385940/
https://www.ncbi.nlm.nih.gov/pubmed/28209733
http://dx.doi.org/10.1091/mbc.E16-12-0865