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Individual S-acylated cysteines differentially contribute to H-Ras endomembrane trafficking and acylation/deacylation cycles

S-acylation/deacylation cycles and vesicular transport are critical for an adequate subcellular distribution of S-acylated Ras proteins. H-Ras is dually acylated on cysteines 181 and 184, but it is unknown how these residues individually contribute to H-Ras trafficking. In this study, we characteriz...

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Detalles Bibliográficos
Autores principales: Pedro, Maria P., Vilcaes, Aldo A., Gomez, Guillermo A., Daniotti, Jose L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385944/
https://www.ncbi.nlm.nih.gov/pubmed/28179458
http://dx.doi.org/10.1091/mbc.E16-08-0603