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Individual S-acylated cysteines differentially contribute to H-Ras endomembrane trafficking and acylation/deacylation cycles
S-acylation/deacylation cycles and vesicular transport are critical for an adequate subcellular distribution of S-acylated Ras proteins. H-Ras is dually acylated on cysteines 181 and 184, but it is unknown how these residues individually contribute to H-Ras trafficking. In this study, we characteriz...
Autores principales: | Pedro, Maria P., Vilcaes, Aldo A., Gomez, Guillermo A., Daniotti, Jose L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385944/ https://www.ncbi.nlm.nih.gov/pubmed/28179458 http://dx.doi.org/10.1091/mbc.E16-08-0603 |
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