Using Mendelian randomization to determine causal effects of maternal pregnancy (intrauterine) exposures on offspring outcomes: Sources of bias and methods for assessing them

Mendelian randomization (MR), the use of genetic variants as instrumental variables (IVs) to test causal effects, is increasingly used in aetiological epidemiology. Few of the methodological developments in MR have considered the specific situation of using genetic IVs to test the causal effect of e...

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Detalles Bibliográficos
Autores principales: Lawlor, Deborah, Richmond, Rebecca, Warrington, Nicole, McMahon, George, Davey Smith, George, Bowden, Jack, Evans, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386135/
https://www.ncbi.nlm.nih.gov/pubmed/28405635
http://dx.doi.org/10.12688/wellcomeopenres.10567.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386135/
https://www.ncbi.nlm.nih.gov/pubmed/28405635
http://dx.doi.org/10.12688/wellcomeopenres.10567.1

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