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Reduced erythrocyte susceptibility and increased host clearance of young parasites slows Plasmodium growth in a murine model of severe malaria

The best correlate of malaria severity in human Plasmodium falciparum (Pf) infection is the total parasite load. Pf-infected humans could control parasite loads by two mechanisms, either decreasing parasite multiplication, or increasing parasite clearance. However, few studies have directly measured...

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Detalles Bibliográficos
Autores principales: Khoury, David S., Cromer, Deborah, Best, Shannon E., James, Kylie R., Sebina, Ismail, Haque, Ashraful, Davenport, Miles P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386191/
https://www.ncbi.nlm.nih.gov/pubmed/25944649
http://dx.doi.org/10.1038/srep09412