SMIFH2 has effects on Formins and p53 that perturb the cell cytoskeleton

Formin proteins are key regulators of the cytoskeleton involved in developmental and homeostatic programs, and human disease. For these reasons, small molecules interfering with Formins’ activity have gained increasing attention. Among them, small molecule inhibitor of Formin Homology 2 domains (SMI...

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Detalles Bibliográficos
Autores principales: Isogai, Tadamoto, van der Kammen, Rob, Innocenti, Metello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386218/
https://www.ncbi.nlm.nih.gov/pubmed/25925024
http://dx.doi.org/10.1038/srep09802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386218/
https://www.ncbi.nlm.nih.gov/pubmed/25925024
http://dx.doi.org/10.1038/srep09802

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