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SMIFH2 has effects on Formins and p53 that perturb the cell cytoskeleton
Formin proteins are key regulators of the cytoskeleton involved in developmental and homeostatic programs, and human disease. For these reasons, small molecules interfering with Formins’ activity have gained increasing attention. Among them, small molecule inhibitor of Formin Homology 2 domains (SMI...
Autores principales: | Isogai, Tadamoto, van der Kammen, Rob, Innocenti, Metello |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386218/ https://www.ncbi.nlm.nih.gov/pubmed/25925024 http://dx.doi.org/10.1038/srep09802 |
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