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Rare variants in fox-1 homolog A (RBFOX1) are associated with lower blood pressure

Many large genome-wide association studies (GWAS) have identified common blood pressure (BP) variants. However, most of the identified BP variants do not overlap with the linkage evidence observed from family studies. We thus hypothesize that multiple rare variants contribute to the observed linkage...

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Detalles Bibliográficos
Autores principales: He, Karen Y., Wang, Heming, Cade, Brian E., Nandakumar, Priyanka, Giri, Ayush, Ware, Erin B., Haessler, Jeffrey, Liang, Jingjing, Smith, Jennifer A., Franceschini, Nora, Le, Thu H., Kooperberg, Charles, Edwards, Todd L., Kardia, Sharon L. R., Lin, Xihong, Chakravarti, Aravinda, Redline, Susan, Zhu, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386302/
https://www.ncbi.nlm.nih.gov/pubmed/28346479
http://dx.doi.org/10.1371/journal.pgen.1006678