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A novel approach for the identification of efficient combination therapies in primary human acute myeloid leukemia specimens

Appropriate culture methods for the interrogation of primary leukemic samples were hitherto lacking and current assays for compound screening are not adapted for large-scale investigation of synergistic combinations. In this study, we report a novel approach that efficiently distills synthetic letha...

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Detalles Bibliográficos
Autores principales: Baccelli, I, Krosl, J, Boucher, G, Boivin, I, Lavallée, V-P, Hébert, J, Lemieux, S, Marinier, A, Sauvageau, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386329/
https://www.ncbi.nlm.nih.gov/pubmed/28211886
http://dx.doi.org/10.1038/bcj.2017.10