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Cellular prion protein mediates early apoptotic proteome alternation and phospho-modification in human neuroblastoma cells

Anti-apoptotic properties of physiological and elevated levels of the cellular prion protein (PrP(c)) under stress conditions are well documented. Yet, detrimental effects of elevated PrP(c) levels under stress conditions, such as exposure to staurosporine (STS) have also been described. In the pres...

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Detalles Bibliográficos
Autores principales: Zafar, Saima, Behrens, Christina, Dihazi, Hassan, Schmitz, Matthias, Zerr, Inga, Schulz-Schaeffer, Walter J, Ramljak, Sanja, Asif, Abdul R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386350/
https://www.ncbi.nlm.nih.gov/pubmed/28102851
http://dx.doi.org/10.1038/cddis.2016.384