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Statins in anthracycline-induced cardiotoxicity: Rac and Rho, and the heartbreakers

Cancer patients receiving anthracycline-based chemotherapy are at risk to develop life-threatening chronic cardiotoxicity with the pathophysiological mechanism of action not fully understood. Besides the most common hypothesis that anthracycline-induced congestive heart failure (CHF) is mainly cause...

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Detalles Bibliográficos
Autores principales: Henninger, Christian, Fritz, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386353/
https://www.ncbi.nlm.nih.gov/pubmed/28102848
http://dx.doi.org/10.1038/cddis.2016.418