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AIF-independent parthanatos in the pathogenesis of dry age-related macular degeneration

Cell death of retinal pigment epithelium (RPE) is characterized as an essential late-stage phenomenon of dry age-related macular degeneration (AMD). The aim of this study was to elucidate the molecular mechanism underlying RPE cell death after exposure to oxidative stress, which occurs often because...

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Detalles Bibliográficos
Autores principales: Jang, Ki-Hong, Do, Yun-Ju, Son, Dongwon, Son, Eunji, Choi, Jun-Sub, Kim, Eunhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386356/
https://www.ncbi.nlm.nih.gov/pubmed/28055012
http://dx.doi.org/10.1038/cddis.2016.437