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Inhibition of Stat3 signaling pathway by nifuroxazide improves antitumor immunity and impairs colorectal carcinoma metastasis

Colorectal carcinoma (CRC) is the one of the most common cancers with considerable metastatic potential, explaining the need for new drug candidates that inhibit tumor metastasis. The signal transducers and activators of the transcription 3 (Stat3) signaling pathway has an important role in CRC and...

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Detalles Bibliográficos
Autores principales: Ye, Ting-Hong, Yang, Fang-Fang, Zhu, Yong-Xia, Li, Ya-Li, Lei, Qian, Song, Xue-Jiao, Xia, Yong, Xiong, Ying, Zhang, Li-Dan, Wang, Ning-Yu, Zhao, Li-Feng, Gou, Hong-Feng, Xie, Yong-Mei, Yang, Sheng-Yong, Yu, Luo-Ting, Yang, Li, Wei, Yu-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386364/
https://www.ncbi.nlm.nih.gov/pubmed/28055016
http://dx.doi.org/10.1038/cddis.2016.452