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Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration

Age-related macular degeneration (AMD) is a devastating neurodegenerative disease and a major cause of blindness in the developed world. Owing to its complexity and the lack of an adequate human model that recapitulates key aspects of the disease, the molecular mechanisms of AMD pathogenesis remain...

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Detalles Bibliográficos
Autores principales: Golestaneh, Nady, Chu, Yi, Xiao, Yang-Yu, Stoleru, Gianna L, Theos, Alexander C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386365/
https://www.ncbi.nlm.nih.gov/pubmed/28055007
http://dx.doi.org/10.1038/cddis.2016.453