Cargando…
Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration
Age-related macular degeneration (AMD) is a devastating neurodegenerative disease and a major cause of blindness in the developed world. Owing to its complexity and the lack of an adequate human model that recapitulates key aspects of the disease, the molecular mechanisms of AMD pathogenesis remain...
Autores principales: | Golestaneh, Nady, Chu, Yi, Xiao, Yang-Yu, Stoleru, Gianna L, Theos, Alexander C |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386365/ https://www.ncbi.nlm.nih.gov/pubmed/28055007 http://dx.doi.org/10.1038/cddis.2016.453 |
Ejemplares similares
-
Pgc-1α repression and high-fat diet induce age-related macular degeneration-like phenotypes in mice
por: Zhang, Meng, et al.
Publicado: (2018) -
Repressed SIRT1/PGC-1α pathway and mitochondrial disintegration in iPSC-derived RPE disease model of age-related macular degeneration
por: Golestaneh, Nady, et al.
Publicado: (2016) -
Dysregulated metabolic pathways in age-related macular degeneration
por: Zhang, Meng, et al.
Publicado: (2020) -
Fundus Autofluorescence and RPE Lipofuscin in Age-Related Macular Degeneration
por: Sparrow, Janet R., et al.
Publicado: (2014) -
Stem cells: a new paradigm for disease modeling and developing therapies for age-related macular degeneration
por: Melville, Heather, et al.
Publicado: (2013)