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Neuronal hemoglobin affects dopaminergic cells' response to stress

Hemoglobin (Hb) is the major protein in erythrocytes and carries oxygen (O(2)) throughout the body. Recently, Hb has been found synthesized in atypical sites, including the brain. Hb is highly expressed in A9 dopaminergic (DA) neurons of the substantia nigra (SN), whose selective degeneration leads...

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Detalles Bibliográficos
Autores principales: Codrich, Marta, Bertuzzi, Maria, Russo, Roberta, Francescatto, Margherita, Espinoza, Stefano, Zentilin, Lorena, Giacca, Mauro, Cesselli, Daniela, Beltrami, Antonio Paolo, Ascenzi, Paolo, Zucchelli, Silvia, Persichetti, Francesca, Leanza, Giampiero, Gustincich, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386368/
https://www.ncbi.nlm.nih.gov/pubmed/28055011
http://dx.doi.org/10.1038/cddis.2016.458